Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-&#945;-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation.

Martin, John; Midgley, Adam; Meran, Soma; Woods, Emma; Bowen, Timothy; Phillips, Aled O; Steadman, Robert

Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-α-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation.

Martin, John; Midgley, Adam; Meran, Soma; Woods, Emma; Bowen, Timothy; Phillips, Aled O; Steadman, Robert.

Afiliación

Martin J; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Midgley A; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Meran S; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Woods E; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Bowen T; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Phillips AO; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Steadman R; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom steadmanr@cf.ac.uk.

J Biol Chem ; 291(26): 13789-801, 2016 Jun 24.

Article en En | MEDLINE | ID: mdl-27143355

Asunto(s)

Moléculas de Adhesión Celular/metabolismo; Diferenciación Celular/fisiología; Miofibroblastos/metabolismo; Proteínas Inhibidoras de Proteinasas Secretoras/metabolismo; Factor de Crecimiento Transformador beta1/metabolismo; Actinas/genética; Actinas/metabolismo; alfa-Globulinas/farmacología; Anticuerpos Monoclonales de Origen Murino/farmacología; Moléculas de Adhesión Celular/genética; Diferenciación Celular/efectos de los fármacos; Línea Celular; Receptores ErbB/genética; Receptores ErbB/metabolismo; Regulación de la Expresión Génica/efectos de los fármacos; Humanos; Receptores de Hialuranos/farmacología; Miofibroblastos/citología; Factor de Crecimiento Transformador beta1/genética

Palabras clave

fibroblast; fibrosis; hyaluronan; myofibroblast; transforming growth factor beta (TGF-B); tumor necrosis factor gene 6

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Moléculas de Adhesión Celular / Diferenciación Celular / Factor de Crecimiento Transformador beta1 / Proteínas Inhibidoras de Proteinasas Secretoras / Miofibroblastos Límite: Humans Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido

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