The heart as an extravascular target of endothelin-1 in particulate matter-induced cardiac dysfunction.

Chan, Elizabeth A W; Buckley, Barbara; Farraj, Aimen K; Thompson, Leslie C

Chan, Elizabeth A W; Buckley, Barbara; Farraj, Aimen K; Thompson, Leslie C.

Afiliación

Chan EA; Oak Ridge Institute for Science and Education (ORISE) Fellow at the National Center for Environmental Assessment, U.S. Environmental Protection Agency (EPA), Research Triangle Park, NC, USA.
Buckley B; National Center for Environmental Assessment, U.S. EPA, Research Triangle Park, NC, USA.
Farraj AK; Environmental Public Health Division, U.S. EPA, Research Triangle Park, NC, USA.
Thompson LC; Environmental Public Health Division, U.S. EPA, Research Triangle Park, NC, USA. Electronic address: thompson.leslie@epa.gov.

Pharmacol Ther ; 165: 63-78, 2016 09.

Article en En | MEDLINE | ID: mdl-27222357

Asunto(s)

Endotelina-1/metabolismo; Cardiopatías/inducido químicamente; Miocardio/metabolismo; Material Particulado/efectos adversos; Animales; Cardiotoxicidad; Antagonistas de los Receptores de Endotelina/uso terapéutico; Endotelina-1/antagonistas & inhibidores; Exposición a Riesgos Ambientales/efectos adversos; Cardiopatías/tratamiento farmacológico; Cardiopatías/metabolismo; Cardiopatías/fisiopatología; Humanos; Transducción de Señal

Palabras clave

Air pollution; Autocrine/paracrine signaling; Cardiac dysfunction; Endothelin-1; Heart; Particulate matter

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Endotelina-1 / Material Particulado / Cardiopatías / Miocardio Límite: Animals / Humans Idioma: En Revista: Pharmacol Ther Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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