The Coronary Artery Disease-associated Coding Variant in Zinc Finger C3HC-type Containing 1 (ZC3HC1) Affects Cell Cycle Regulation.

Jones, Peter D; Kaiser, Michael A; Ghaderi Najafabadi, Maryam; McVey, David G; Beveridge, Allan J; Schofield, Christine L; Samani, Nilesh J; Webb, Tom R

Jones, Peter D; Kaiser, Michael A; Ghaderi Najafabadi, Maryam; McVey, David G; Beveridge, Allan J; Schofield, Christine L; Samani, Nilesh J; Webb, Tom R.

Afiliación

Jones PD; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
Kaiser MA; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
Ghaderi Najafabadi M; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
McVey DG; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
Beveridge AJ; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
Schofield CL; Horizon Discovery Limited, 7100 Cambridge Research Park, Waterbeach, Cambridge CB25 9TL, United Kingdom.
Samani NJ; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and.
Webb TR; From the Department of Cardiovascular Sciences and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, University of Leicester, Leicester, LE3 9QP and tw126@le.ac.uk.

J Biol Chem ; 291(31): 16318-27, 2016 07 29.

Article en En | MEDLINE | ID: mdl-27226629

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales; Proteínas de Ciclo Celular; Enfermedad de la Arteria Coronaria; Sitios Genéticos; Desequilibrio de Ligamiento; Mitosis/genética; Proteínas Nucleares; Polimorfismo Genético; Proteínas Adaptadoras Transductoras de Señales/genética; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Línea Celular; Enfermedad de la Arteria Coronaria/genética; Enfermedad de la Arteria Coronaria/metabolismo; Ciclina B1/genética; Ciclina B1/metabolismo; Humanos; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Dedos de Zinc/genética

Palabras clave

CAD; cell cycle; coronary artery disease; cyclin; cyclin-dependent kinase (CDK); genome editing; phosphorylation; protein structure; rAAV; single-nucleotide polymorphism (SNP)

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polimorfismo Genético / Enfermedad de la Arteria Coronaria / Proteínas Nucleares / Desequilibrio de Ligamiento / Proteínas de Ciclo Celular / Proteínas Adaptadoras Transductoras de Señales / Sitios Genéticos / Mitosis Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article

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