Granzyme B-truncated VEGF fusion protein represses angiogenesis and tumor growth of OSCC.

Lv, X-Z; Zheng, M-Y; Lin, Z-Q; Zhao, M; Wang, H; Zeng, W-S

Lv, X-Z; Zheng, M-Y; Lin, Z-Q; Zhao, M; Wang, H; Zeng, W-S.

Afiliación

Lv XZ; Department Oral & Head and Neck Surgery, Nan Fang Hospital, Southern Medical University, Guangzhou, China.
Zheng MY; Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangzhou, China.
Lin ZQ; Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangzhou, China.
Zhao M; Department Oral & Head and Neck Surgery, Nan Fang Hospital, Southern Medical University, Guangzhou, China.
Wang H; Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangzhou, China.
Zeng WS; Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangzhou, China. zengws@smu.edu.cn.

Oral Dis ; 22(7): 688-96, 2016 Oct.

Article en En | MEDLINE | ID: mdl-27291760

Asunto(s)

Carcinoma de Células Escamosas/tratamiento farmacológico; Carcinoma de Células Escamosas/patología; Granzimas/farmacología; Neoplasias de la Boca/tratamiento farmacológico; Neoplasias de la Boca/patología; Neovascularización Patológica/tratamiento farmacológico; Factor A de Crecimiento Endotelial Vascular/farmacología; Inhibidores de la Angiogénesis/farmacología; Animales; Células Cultivadas; Embrión de Pollo; Humanos; Ratones; Ratones Desnudos; Neoplasias de la Lengua/tratamiento farmacológico

Palabras clave

fusion protein; granzyme B (GrB); oral squamous cell carcinoma (OSCC); tumor therapy; vascular endothelial growth factor (VEGF)

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas / Factor A de Crecimiento Endotelial Vascular / Granzimas / Neovascularización Patológica Límite: Animals / Humans Idioma: En Revista: Oral Dis Asunto de la revista: ODONTOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China

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