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[Molecular imaging in neurological diseases]. / Molekulare Bildgebung bei neurologischen Erkrankungen.
Reimold, M; la Fougère, C.
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  • Reimold M; Abteilung Nuklearmedizin und Klinische Molekulare Bildgebung, Department Radiologie, Universitätsklinikum Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Deutschland.
  • la Fougère C; Abteilung Nuklearmedizin und Klinische Molekulare Bildgebung, Department Radiologie, Universitätsklinikum Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Deutschland. christian.lafougere@med.uni-tuebingen.de.
Radiologe ; 56(7): 580-7, 2016 Jul.
Article en De | MEDLINE | ID: mdl-27306201
In neurodegeneration and in neuro-oncology, the standard imaging procedure, magnetic resonance imaging (MRI), shows limited sensitivity and specificity. Molecular imaging with specific positron-emission tomography (PET) and single-photon emission computed tomography (SPECT) tracers allows various molecular targets and metabolic processes to be assessed and is thus a valuable adjunct to MRI. Two important examples are referred to here: amino acid transport for neuro-oncological issues, and the recently approved PET tracers for detecting amyloid depositions during the preclinical stage of Alzheimer's disease. This review discusses the clinical relevance and indications for the following nuclear medicine imaging procedures: amyloid PET, (18)F-fluorodeoxyglucose (FDG)-PET, and dopamine transporter (DaT)-SPECT for the diagnosis of dementia and the differential diagnosis of Parkinson's disease, in addition to amino acid PET for the diagnosis of brain tumors and somatostatin receptor imaging in meningioma.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Tomografía Computarizada de Emisión / Radiofármacos / Enfermedades Neurodegenerativas / Imagen Molecular Tipo de estudio: Diagnostic_studies / Evaluation_studies Límite: Humans Idioma: De Revista: Radiologe Año: 2016 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Tomografía Computarizada de Emisión / Radiofármacos / Enfermedades Neurodegenerativas / Imagen Molecular Tipo de estudio: Diagnostic_studies / Evaluation_studies Límite: Humans Idioma: De Revista: Radiologe Año: 2016 Tipo del documento: Article