The cognitive impairment induced by zinc deficiency in rats aged 0â¼2 months related to BDNF DNA methylation changes in the hippocampus.

Hu, Yan-Dan; Pang, Wei; He, Cong-Cong; Lu, Hao; Liu, Wei; Wang, Zi-Yu; Liu, Yan-Qiang; Huang, Cheng-Yu; Jiang, Yu-Gang

The cognitive impairment induced by zinc deficiency in rats aged 0â¼2 months related to BDNF DNA methylation changes in the hippocampus.

Hu, Yan-Dan; Pang, Wei; He, Cong-Cong; Lu, Hao; Liu, Wei; Wang, Zi-Yu; Liu, Yan-Qiang; Huang, Cheng-Yu; Jiang, Yu-Gang.

Afiliación

Hu YD; a Department of Nutrition , Tianjin Institute of Health and Environmental Medicine , Tianjin 300050 , China.
Pang W; b Department of Nutrition and Food Hygiene , West China School of Public Health, Sichuan University , Chengdu 610041 , China.
He CC; a Department of Nutrition , Tianjin Institute of Health and Environmental Medicine , Tianjin 300050 , China.
Lu H; c College of Life Science, Nan Kai University , Tianjin 300000 , China.
Liu W; b Department of Nutrition and Food Hygiene , West China School of Public Health, Sichuan University , Chengdu 610041 , China.
Wang ZY; a Department of Nutrition , Tianjin Institute of Health and Environmental Medicine , Tianjin 300050 , China.
Liu YQ; a Department of Nutrition , Tianjin Institute of Health and Environmental Medicine , Tianjin 300050 , China.
Huang CY; c College of Life Science, Nan Kai University , Tianjin 300000 , China.
Jiang YG; b Department of Nutrition and Food Hygiene , West China School of Public Health, Sichuan University , Chengdu 610041 , China.

Nutr Neurosci ; 20(9): 519-525, 2017 Nov.

Article en En | MEDLINE | ID: mdl-27329329

Asunto(s)

Factor Neurotrófico Derivado del Encéfalo/metabolismo; Disfunción Cognitiva/etiología; Metilación de ADN; Enfermedades Carenciales/fisiopatología; Hipocampo/metabolismo; Neuronas/metabolismo; Zinc/deficiencia; Animales; Reacción de Prevención; Conducta Animal; Factor Neurotrófico Derivado del Encéfalo/genética; ADN (Citosina-5-)-Metiltransferasa 1/genética; ADN (Citosina-5-)-Metiltransferasa 1/metabolismo; ADN (Citosina-5-)-Metiltransferasas/genética; ADN (Citosina-5-)-Metiltransferasas/metabolismo; ADN Metiltransferasa 3A; Enfermedades Carenciales/sangre; Enfermedades Carenciales/metabolismo; Epigénesis Genética; Exones; Femenino; Regulación del Desarrollo de la Expresión Génica; Lactancia; Masculino; Fenómenos Fisiologicos Nutricionales Maternos; ARN Mensajero/metabolismo; Distribución Aleatoria; Ratas; Zinc/sangre; Zinc/metabolismo

Palabras clave

BDNF gene transcription; DNA methylation; Hippocampus; Learning and memory; Zinc deficiency

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Zinc / Factor Neurotrófico Derivado del Encéfalo / Metilación de ADN / Enfermedades Carenciales / Disfunción Cognitiva / Hipocampo / Neuronas Límite: Animals Idioma: En Revista: Nutr Neurosci Asunto de la revista: CIENCIAS DA NUTRICAO / NEUROLOGIA Año: 2017 Tipo del documento: Article País de afiliación: China

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