Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer.
Curr Opin Pharmacol
; 29: 47-53, 2016 08.
Article
en En
| MEDLINE
| ID: mdl-27366992
ABSTRACT
Normal and tumor cells shed vesicles to the environment. Within the large family of extracellular vesicles, exosomes and microvesicles have attracted much attention in the recent years. Their interest ranges from mediators of cancer progression, inflammation, immune regulation and metastatic niche regulation, to non-invasive biomarkers of disease. In this respect, the procedures to purify and analyze extracellular vesicles have quickly evolved and represent a source of variability for data integration in the field. In this review, we provide an updated view of the potential of exosomes and microvesicles as biomarkers and the available technologies for their isolation.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Exosomas
/
Vesículas Extracelulares
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Opin Pharmacol
Asunto de la revista:
FARMACOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
España