Clinical factors that affect the outcomes after anatomical versus non-anatomical resection for hepatocellular carcinoma.
Surg Today
; 47(2): 193-201, 2017 Feb.
Article
en En
| MEDLINE
| ID: mdl-27502598
ABSTRACT
PURPOSE:
For hepatocellular carcinoma (HCC), the superiority of anatomical resection (AR) over non-anatomical resection (NR) is still controversial. In this study, we assessed the potential benefits of AR for HCC.METHODS:
We enrolled 173 consecutive patients with HCC who underwent hepatectomy in our hospital from August 2003 to May 2013 and compared the outcomes for the AR group (n = 125) with those for the NR group (n = 48).RESULTS:
The median observational period was 790 days. The 1- and 2-year overall survival (OS) rates were 92.1 and 85.8 %, respectively; the 1- and 2-year disease-free survival (DFS) rates were 78.2 and 63.0 %, respectively. The AR and NR groups did not significantly differ in the OS or DFS. However, the 2-year DFS was significantly better for the AR group than the NR group among HCV patients (68.2 vs. 32.2 %; P = 0.004) and patients with alpha-fetoprotein (AFP) within the normal range (<20 ng/ml; 76.7 vs. 60.9 %; P = 0.031), total bilirubin <0.8 mg/dl (70.8 vs. 47.0 %; P = 0.034), and tumors 2-5 cm in diameter (82.0 vs. 62.5 %; P = 0.025).CONCLUSIONS:
If a patient is HCV-negative, has low AFP, low total bilirubin, or a tumor diameter of 2-5 cm, AR is recommended.Palabras clave
Texto completo:
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Bases de datos:
MEDLINE
Asunto principal:
Carcinoma Hepatocelular
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Hepatectomía
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Neoplasias Hepáticas
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Surg Today
Año:
2017
Tipo del documento:
Article
País de afiliación:
Japón