Identification of an Essential Region for Translocation of Clostridium difficile Toxin B.

Chen, Shuyi; Wang, Haiying; Gu, Huawei; Sun, Chunli; Li, Shan; Feng, Hanping; Wang, Jufang

Chen, Shuyi; Wang, Haiying; Gu, Huawei; Sun, Chunli; Li, Shan; Feng, Hanping; Wang, Jufang.

Afiliación

Chen S; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. shuyichan@foxmail.com.
Wang H; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. yingzi224926@163.com.
Gu H; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. guhuawei1990@163.com.
Sun C; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. chunlis@163.com.
Li S; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. lishan@scut.edu.cn.
Feng H; Department of Microbial Pathogenesis, University of Maryland Dental School, Baltimore, MD 21201, USA. hfeng@umaryland.edu.
Wang J; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China. jufwang@scut.edu.cn.

Toxins (Basel) ; 8(8)2016 08 15.

Article en En | MEDLINE | ID: mdl-27537911

Asunto(s)

Proteínas Bacterianas/metabolismo; Toxinas Bacterianas/metabolismo; Clostridioides difficile/metabolismo; Enterocolitis Seudomembranosa/microbiología; Factores de Virulencia/metabolismo; Animales; Proteínas Bacterianas/química; Proteínas Bacterianas/genética; Toxinas Bacterianas/química; Toxinas Bacterianas/genética; Línea Celular Tumoral; Chlorocebus aethiops; Clostridioides difficile/genética; Clostridioides difficile/patogenicidad; Endocitosis; Enterocolitis Seudomembranosa/metabolismo; Enterocolitis Seudomembranosa/patología; Ratones Endogámicos BALB C; Mutación; Dominios Proteicos; Estabilidad Proteica; Estructura Secundaria de Proteína; Transporte de Proteínas; Proteolisis; Células Vero; Factores de Virulencia/química

Palabras clave

Clostridium difficile; conformational change; endocytosis; toxin; translocation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Toxinas Bacterianas / Enterocolitis Seudomembranosa / Clostridioides difficile / Factores de Virulencia Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Toxins (Basel) Año: 2016 Tipo del documento: Article País de afiliación: China

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