Bowel dysfunction following pullthrough surgery is associated with an overabundance of nitrergic neurons in Hirschsprung disease.

Cheng, Lily S; Schwartz, Dana M; Hotta, Ryo; Graham, Hannah K; Goldstein, Allan M

Cheng, Lily S; Schwartz, Dana M; Hotta, Ryo; Graham, Hannah K; Goldstein, Allan M.

Afiliación

Cheng LS; Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114; Department of Surgery, University of California San Francisco, 500 Parnassus Ave, San Francisco, CA 94143.
Schwartz DM; Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114.
Hotta R; Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114.
Graham HK; Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114.
Goldstein AM; Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114. Electronic address: agoldstein@partners.org.

J Pediatr Surg ; 51(11): 1834-1838, 2016 Nov.

Article en En | MEDLINE | ID: mdl-27570241

Asunto(s)

Procedimientos Quirúrgicos del Sistema Digestivo/métodos; Enfermedad de Hirschsprung/cirugía; Plexo Mientérico/metabolismo; Neuronas Nitrérgicas/patología; Óxido Nítrico Sintasa de Tipo I/metabolismo; Animales; Femenino; Enfermedad de Hirschsprung/diagnóstico; Humanos; Inmunohistoquímica; Lactante; Recién Nacido; Masculino; Ratones; Ratones Endogámicos C57BL; Plexo Mientérico/patología; Neuronas Nitrérgicas/metabolismo

Palabras clave

Calretinin; Constipation; Enteric nervous system; Hirschsprung disease; Myenteric plexus; Nitric oxide synthase

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos del Sistema Digestivo / Neuronas Nitrérgicas / Óxido Nítrico Sintasa de Tipo I / Enfermedad de Hirschsprung / Plexo Mientérico Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Infant / Male / Newborn Idioma: En Revista: J Pediatr Surg Año: 2016 Tipo del documento: Article

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