Does manual T-wave window adjustment affect microvolt T-wave alternans results in patients with structural heart disease?
J Electrocardiol
; 49(6): 967-972, 2016.
Article
en En
| MEDLINE
| ID: mdl-27597389
ABSTRACT
INTRODUCTION:
Microvolt T-wave alternans (MTWA) analysis can identify patients at low risk of sudden cardiac death who might not benefit from an implantable cardioverter-defibrillator (ICD). Current spectral methodology for performing MTWA analysis may "miss" part of the T-wave in patients with QT prolongation. The value of T-wave window adjustment in patients with structural heart disease has not been studied.METHODS:
We assembled MTWA data from 5 prior prospective studies including 170 patients with reduced left ventricular ejection fraction, adjusted the T-wave window to include the entire T-wave, and reanalyzed MTWA.RESULTS:
Of 170 patients, 43% required T-wave window adjustment. Only 3 of 170 patients (1.8%) had a clinically significant change in MTWA results.CONCLUSIONS:
In 98.2% of patients, T-wave window adjustment did not improve the accuracy of MTWA analysis. Spectral MTWA as currently implemented remains effective for identifying patients with structural heart disease unlikely to benefit from ICD therapy.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Algoritmos
/
Disfunción Ventricular Izquierda
/
Electrocardiografía
/
Cardiomiopatías
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Límite:
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Electrocardiol
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos