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Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aß42/Aß40 ratio.
Xu, Ting-Hai; Yan, Yan; Kang, Yanyong; Jiang, Yi; Melcher, Karsten; Xu, H Eric.
Afiliación
  • Xu TH; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research In
  • Yan Y; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research In
  • Kang Y; Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research Institute , Grand Rapids, MI, USA.
  • Jiang Y; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai, China.
  • Melcher K; Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research Institute , Grand Rapids, MI, USA.
  • Xu HE; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research In
Cell Discov ; 2: 16026, 2016.
Article en En | MEDLINE | ID: mdl-27625790
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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Cell Discov Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Cell Discov Año: 2016 Tipo del documento: Article