Anticonvulsive Activity in Audiogenic DBA/2 Mice of 1,4-Benzodiazepines and 1,5-Benzodiazepines with Different Activities at Cerebellar Granule Cell GABA<sub>A</sub> Receptors.

Gatta, Elena; Cupello, Aroldo; Di Braccio, Mario; Grossi, Giancarlo; Robello, Mauro; Scicchitano, Francesca; Russo, Emilio; De Sarro, Giovambattista

Anticonvulsive Activity in Audiogenic DBA/2 Mice of 1,4-Benzodiazepines and 1,5-Benzodiazepines with Different Activities at Cerebellar Granule Cell GABA_A Receptors.

Gatta, Elena; Cupello, Aroldo; Di Braccio, Mario; Grossi, Giancarlo; Robello, Mauro; Scicchitano, Francesca; Russo, Emilio; De Sarro, Giovambattista.

Afiliación

Gatta E; Department of Physics, University of Genova, Via Dodecaneso 33, 16146, Genoa, Italy.
Cupello A; Department of Physics, University of Genova, Via Dodecaneso 33, 16146, Genoa, Italy. aroldo.cupello@unige.it.
Di Braccio M; Department of Pharmacy, Pharmaceutical Chemistry Section, University of Genova, 16132, Genoa, Italy.
Grossi G; Department of Pharmacy, Pharmaceutical Chemistry Section, University of Genova, 16132, Genoa, Italy.
Robello M; Department of Physics, University of Genova, Via Dodecaneso 33, 16146, Genoa, Italy.
Scicchitano F; Science of Health Department, School of Medicine, University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.
Russo E; Science of Health Department, School of Medicine, University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.
De Sarro G; Science of Health Department, School of Medicine, University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.

J Mol Neurosci ; 60(4): 539-547, 2016 Dec.

Article en En | MEDLINE | ID: mdl-27629561

Asunto(s)

Anticonvulsivantes/farmacología; Benzodiazepinas/farmacología; Cerebelo/metabolismo; Epilepsia Generalizada/tratamiento farmacológico; Neuronas/efectos de los fármacos; Receptores de GABA-A/metabolismo; Potenciales de Acción; Animales; Anticonvulsivantes/administración & dosificación; Anticonvulsivantes/síntesis química; Anticonvulsivantes/uso terapéutico; Benzodiazepinas/administración & dosificación; Benzodiazepinas/síntesis química; Benzodiazepinas/uso terapéutico; Células Cultivadas; Cerebelo/citología; Cloruros/metabolismo; Ratones; Ratones Endogámicos DBA; Neuronas/metabolismo; Neuronas/fisiología; Ratas; Ratas Sprague-Dawley

Palabras clave

1,4-Benzodiazepines and 1,5-benzodiazepines; Anticonvulsive action; Audiogenic DBA/2 mice; Cerebellar granule cells; Cerebellum; Epilepsy

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Bases de datos: MEDLINE Asunto principal: Benzodiazepinas / Cerebelo / Epilepsia Generalizada / Receptores de GABA-A / Anticonvulsivantes / Neuronas Límite: Animals Idioma: En Revista: J Mol Neurosci Asunto de la revista: BIOLOGIA MOLECULAR / NEUROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Italia

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