Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity.

van Moorsel, Dirk; Hansen, Jan; Havekes, Bas; Scheer, Frank A J L; Jörgensen, Johanna A; Hoeks, Joris; Schrauwen-Hinderling, Vera B; Duez, Helene; Lefebvre, Philippe; Schaper, Nicolaas C; Hesselink, Matthijs K C; Staels, Bart; Schrauwen, Patrick

van Moorsel, Dirk; Hansen, Jan; Havekes, Bas; Scheer, Frank A J L; Jörgensen, Johanna A; Hoeks, Joris; Schrauwen-Hinderling, Vera B; Duez, Helene; Lefebvre, Philippe; Schaper, Nicolaas C; Hesselink, Matthijs K C; Staels, Bart; Schrauwen, Patrick.

Afiliación

van Moorsel D; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands; Department of Internal Medicine, Division of Endocrinology, Maastricht University Medi
Hansen J; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands.
Havekes B; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands; Department of Internal Medicine, Division of Endocrinology, Maastricht University Medi
Scheer FAJL; Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA.
Jörgensen JA; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands.
Hoeks J; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands.
Schrauwen-Hinderling VB; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands; Department of Radiology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Ma
Duez H; Univ Lille, Inserm, Institut Pasteur de Lille, UMR1011-EGID, BP245, 59019 Lille, France.
Lefebvre P; Univ Lille, Inserm, Institut Pasteur de Lille, UMR1011-EGID, BP245, 59019 Lille, France.
Schaper NC; Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Maastricht, The Netherlands; CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center, Maastricht, The Netherlands.
Hesselink MKC; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands.
Staels B; Univ Lille, Inserm, Institut Pasteur de Lille, UMR1011-EGID, BP245, 59019 Lille, France.
Schrauwen P; Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands. Electronic address: p.schrauwen@maastrichtuniversity.nl.

Mol Metab ; 5(8): 635-645, 2016 Aug.

Article en En | MEDLINE | ID: mdl-27656401

Palabras clave

BMAL1, brain and muscle ARNT-like 1; BMI, body mass index; Biological rhythm; CLOCK, circadian locomotor output cycles kaput; CRY, cryptochrome; Energy metabolism; FCCP, carbonyl cyanide-4-trifluoromethoxyphenylhydrazone; Mitochondria; Molecular clock; NADH, reduced nicotinamide adenine dinucleotide; Oxidative capacity; PER, period; RER, respiratory exchange ratio; RT-QPCR, Real-Time Quantitative Polymerase Chain Reaction; Skeletal muscle; T2DM, type 2 diabetes mellitus; TCA cycle, tricarboxylic acid cycle

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