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The importance of protein binding for the in vitro-in vivo extrapolation (IVIVE)-example of ibuprofen, a highly protein-bound substance.
Mielke, H; Di Consiglio, E; Kreutz, R; Partosch, F; Testai, E; Gundert-Remy, U.
Afiliación
  • Mielke H; Federal Institute for Risk Assessment, Berlin, Germany. hans.mielke@bfr.bund.de.
  • Di Consiglio E; Istituto Superiore di Sanità, Environment and Primary Prevention Department, Mechanisms of Toxicity Unit, Rome, Italy.
  • Kreutz R; Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Partosch F; Institute for Occupational, Social and Environmental Medicine, Medical School, Göttingen, Germany.
  • Testai E; Istituto Superiore di Sanità, Environment and Primary Prevention Department, Mechanisms of Toxicity Unit, Rome, Italy.
  • Gundert-Remy U; Federal Institute for Risk Assessment, Berlin, Germany.
Arch Toxicol ; 91(4): 1663-1670, 2017 Apr.
Article en En | MEDLINE | ID: mdl-27770144
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antiinflamatorios no Esteroideos / Ibuprofeno / Hígado / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2017 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antiinflamatorios no Esteroideos / Ibuprofeno / Hígado / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2017 Tipo del documento: Article País de afiliación: Alemania