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Branched Gold Nanoparticle Coating of Clostridium novyi-NT Spores for CT-Guided Intratumoral Injection.
Park, Wooram; Cho, Soojeong; Huang, Xiaoke; Larson, Andrew C; Kim, Dong-Hyun.
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  • Park W; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
  • Cho S; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
  • Huang X; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
  • Larson AC; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
  • Kim DH; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.
Small ; 13(5)2017 02.
Article en En | MEDLINE | ID: mdl-27862936
Branched gold nanoparticle (BGNP)-coated Clostridium novyi-NT (C. novyi-NT) spores are developed for computed tomography (CT)-guided bacteriolytic tumor therapy. The BGNP-coated spores are successfully injected into a tumor site under CT image guidance. As a result, a strong antitumor effect is observed in a PC3 prostate tumor-bearing mouse model.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Esporas Bacterianas / Nanopartículas del Metal / Oro Tipo de estudio: Guideline Idioma: En Revista: Small Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Esporas Bacterianas / Nanopartículas del Metal / Oro Tipo de estudio: Guideline Idioma: En Revista: Small Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos