A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System.

Matsuura, Mariko F; Winiger, Christian B; Shaw, Ryan W; Kim, Myong-Jung; Kim, Myong-Sang; Daugherty, Ashley B; Chen, Fei; Moussatche, Patricia; Moses, Jennifer D; Lutz, Stefan; Benner, Steven A

Matsuura, Mariko F; Winiger, Christian B; Shaw, Ryan W; Kim, Myong-Jung; Kim, Myong-Sang; Daugherty, Ashley B; Chen, Fei; Moussatche, Patricia; Moses, Jennifer D; Lutz, Stefan; Benner, Steven A.

Afiliación

Matsuura MF; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Winiger CB; Department of Chemistry, University of Florida , Gainesville, Florida 32611, United States.
Shaw RW; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Kim MJ; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Kim MS; Firebird Biomolecular Sciences, LLC , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Daugherty AB; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Chen F; Firebird Biomolecular Sciences, LLC , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Moussatche P; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Moses JD; Firebird Biomolecular Sciences, LLC , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.
Lutz S; Department of Chemistry, Emory University , 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Benner SA; The Foundation for Applied Molecular Evolution (FfAME) , 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States.

ACS Synth Biol ; 6(3): 388-394, 2017 03 17.

Article en En | MEDLINE | ID: mdl-27935283

Asunto(s)

Drosophila melanogaster/genética; Nucleósidos/genética; Fosfotransferasas (Aceptor de Grupo Alcohol)/genética; Polimorfismo de Nucleótido Simple/genética; Aminoácidos/genética; Animales; Emparejamiento Base/genética; Enlace de Hidrógeno; Fosforilación/genética; Polifosfatos/metabolismo; Pirimidinas/metabolismo; Triazinas/metabolismo

Palabras clave

artificial metabolism; artificially expanded genetic information system; enzyme engineering; nucleoside/nucleotide analogues; nucleotide biosynthesis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fosfotransferasas (Aceptor de Grupo Alcohol) / Polimorfismo de Nucleótido Simple / Drosophila melanogaster / Nucleósidos Límite: Animals Idioma: En Revista: ACS Synth Biol Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google