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Engineering extrinsic disorder to control protein activity in living cells.
Dagliyan, Onur; Tarnawski, Miroslaw; Chu, Pei-Hsuan; Shirvanyants, David; Schlichting, Ilme; Dokholyan, Nikolay V; Hahn, Klaus M.
Afiliación
  • Dagliyan O; Program in Molecular and Cellular Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Tarnawski M; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Chu PH; Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Shirvanyants D; Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany.
  • Schlichting I; Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Dokholyan NV; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Hahn KM; Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany.
Science ; 354(6318): 1441-1444, 2016 12 16.
Article en En | MEDLINE | ID: mdl-27980211

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Familia-src Quinasas / Luz Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Familia-src Quinasas / Luz Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos