Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors.

McCoull, William; Hennessy, Edward J; Blades, Kevin; Chuaqui, Claudio; Dowling, James E; Ferguson, Andrew D; Goldberg, Frederick W; Howe, Nicholas; Jones, Christopher R; Kemmitt, Paul D; Lamont, Gillian; Varnes, Jeffrey G; Ward, Richard A; Yang, Bin.

Afiliación

McCoull W; AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.
Hennessy EJ; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.
Blades K; AstraZeneca , Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K.
Chuaqui C; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.
Dowling JE; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.
Ferguson AD; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.
Goldberg FW; AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.
Howe N; AstraZeneca , Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K.
Jones CR; AstraZeneca , Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K.
Kemmitt PD; AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.
Lamont G; AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.
Varnes JG; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.
Ward RA; AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.
Yang B; AstraZeneca , Gatehouse Park, Waltham, Massachusetts 02451, United States.