The impact of air pollution in the Southern Bohemia Region on fetuses and newborns.
Neuro Endocrinol Lett
; 37(suppl 2): 52-57, 2016 Dec.
Article
en En
| MEDLINE
| ID: mdl-28233961
ABSTRACT
Air pollution with increased concentrations of carcinogenic polycyclic aromatic hydrocarbons (c-PAHs, represented by benzo[a]pyrene, B[a]P) affect fetal development, reduce birth weights (LBW) of newborns, and increases intrauterine growth retardation (IUGR). The Southern Bohemia Region is believed to be one of the least air polluted regions in the Czech Republic. Monitoring air pollution in the city of Ceské Budejovice from 2011-2015, PM2.5 (particulate matter <2.5 µm) decreased from 20.3 ± 14.5 µg/m3 to 14.3 ± 8.6 µg/m3, but concentrations of B[a]P did not change between the years 2007-2015 1.5 ± 0.6 ng/m3 vs. 1.4 ± 1.4 ng/m3. Higher B[a]P concentrations the winter induce genetic damage in newborns, increase frequency of micronuclei (chromosomal aberrations), deregulate genes for immunity in umbilical cord blood, and increase incidence of IUGR and LBW in newborns.
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Bases de datos:
MEDLINE
Asunto principal:
Benzo(a)pireno
/
Aberraciones Cromosómicas
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Exposición Materna
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Contaminantes Atmosféricos
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Contaminación del Aire
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Material Particulado
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Retardo del Crecimiento Fetal
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Enfermedades del Recién Nacido
Límite:
Adult
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Female
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Humans
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Newborn
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Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
Neuro Endocrinol Lett
Año:
2016
Tipo del documento:
Article
País de afiliación:
República Checa