l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway.

Kurauchi, Yuki; Mokudai, Koichi; Mori, Asami; Sakamoto, Kenji; Nakahara, Tsutomu; Morita, Masahiko; Kamimura, Ayako; Ishii, Kunio

Kurauchi, Yuki; Mokudai, Koichi; Mori, Asami; Sakamoto, Kenji; Nakahara, Tsutomu; Morita, Masahiko; Kamimura, Ayako; Ishii, Kunio.

Afiliación

Kurauchi Y; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan. Electronic address: kurauchy@kumamoto-u.ac.jp.
Mokudai K; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Mori A; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Sakamoto K; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Nakahara T; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Morita M; Healthcare Products Development Center, Kyowa Hakko Bio Co., Ltd., 2 Miyukigaoka, Tsukuba-shi, Ibaraki 305-0841, Japan.
Kamimura A; Healthcare Products Development Center, Kyowa Hakko Bio Co., Ltd., 2 Miyukigaoka, Tsukuba-shi, Ibaraki 305-0841, Japan.
Ishii K; Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.

J Pharmacol Sci ; 133(3): 146-155, 2017 Mar.

Article en En | MEDLINE | ID: mdl-28325558

Asunto(s)

Circulación Cerebrovascular/efectos de los fármacos; Citrulina/farmacología; Depresión de Propagación Cortical/fisiología; Óxido Nítrico/fisiología; Prostaglandinas/fisiología; Animales; GMP Cíclico/fisiología; Masculino; Ratas Sprague-Dawley

Palabras clave

Cerebral blood flow; Cortical spreading depression; Nitric oxide; Prostanoids; l-Citrulline

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Depresión de Propagación Cortical / Circulación Cerebrovascular / Prostaglandinas / Citrulina / Óxido Nítrico Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2017 Tipo del documento: Article

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