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Dihydrocelastrol inhibits multiple myeloma cell proliferation and promotes apoptosis through ERK1/2 and IL-6/STAT3 pathways in vitro and in vivo.
Hu, Liangning; Wu, Huiqun; Li, Bo; Song, Dongliang; Yang, Guang; Chen, Gege; Xie, Bingqian; Xu, Zhijian; Zhang, Yong; Yu, Dandan; Hou, Jun; Xiao, Wenqin; Sun, Xi; Chang, Gaomei; Zhang, Yiwen; Gao, Lu; Dai, Bojie; Tao, Yi; Shi, Jumei; Zhu, Weiliang.
Afiliación
  • Hu L; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Wu H; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Li B; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Song D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Yang G; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Chen G; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Xie B; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Xu Z; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang Y; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Yu D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Hou J; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Xiao W; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Sun X; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Chang G; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Zhang Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Gao L; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Dai B; College of Life Science and Technology, Tongji University, Shanghai 200092, China.
  • Tao Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Shi J; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Zhu W; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Acta Biochim Biophys Sin (Shanghai) ; 49(5): 420-427, 2017 May 01.
Article en En | MEDLINE | ID: mdl-28338993
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triterpenos / Interleucina-6 / Apoptosis / Sistema de Señalización de MAP Quinasas / Factor de Transcripción STAT3 / Mieloma Múltiple Límite: Animals Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triterpenos / Interleucina-6 / Apoptosis / Sistema de Señalización de MAP Quinasas / Factor de Transcripción STAT3 / Mieloma Múltiple Límite: Animals Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: China