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Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian; Edbauer, Dieter.
Afiliación
  • Zhou Q; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Lehmer C; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
  • Michaelsen M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Mori K; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Alterauge D; Biomedical Center, Biochemistry, Ludwig Maximilians-Universität München, Planegg-Martinsried, Germany.
  • Baumjohann D; Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Schludi MH; Institute for Immunology, Biomedical Center Munich, Ludwig Maximilians-Universität München, Planegg-Martinsried, Germany.
  • Greiling J; Institute for Immunology, Biomedical Center Munich, Ludwig Maximilians-Universität München, Planegg-Martinsried, Germany.
  • Farny D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Flatley A; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
  • Feederle R; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • May S; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Schreiber F; Monoclonal Antibody Core Facility and Research Group, Institute for Diabetes and Obesity, Helmholtz Zentrum München German Research Center for Environmental Health (GmbH), Munich, Germany.
  • Arzberger T; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Kuhm C; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
  • Klopstock T; Monoclonal Antibody Core Facility and Research Group, Institute for Diabetes and Obesity, Helmholtz Zentrum München German Research Center for Environmental Health (GmbH), Munich, Germany.
  • Hermann A; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Haass C; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
EMBO Mol Med ; 9(5): 687-702, 2017 05.
Article en En | MEDLINE | ID: mdl-28351931

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Agregación Patológica de Proteínas / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Inmunoterapia / Anticuerpos Límite: Animals / Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Agregación Patológica de Proteínas / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Inmunoterapia / Anticuerpos Límite: Animals / Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: Alemania