Examining procedural working memory processing in obsessive-compulsive disorder.
Psychiatry Res
; 253: 197-204, 2017 07.
Article
en En
| MEDLINE
| ID: mdl-28390295
ABSTRACT
Previous research has suggested that a deficit in working memory might underlie the difficulty of obsessive-compulsive disorder (OCD) patients to control their thoughts and actions. However, a recent meta-analyses found only small effect sizes for working memory deficits in OCD. Recently, a distinction has been made between declarative and procedural working memory. Working memory in OCD was tested mostly using declarative measurements. However, OCD symptoms typically concerns actions, making procedural working-memory more relevant. Here, we tested the operation of procedural working memory in OCD. Participants with OCD and healthy controls performed a battery of choice reaction tasks under high and low procedural working memory demands. Reaction-times (RT) were estimated using ex-Gaussian distribution fitting, revealing no group differences in the size of the RT distribution tail (i.e., τ parameter), known to be sensitive to procedural working memory manipulations. Group differences, unrelated to working memory manipulations, were found in the leading-edge of the RT distribution and analyzed using a two-stage evidence accumulation model. Modeling results suggested that perceptual difficulties might underlie the current group differences. In conclusion, our results suggest that procedural working-memory processing is most likely intact in OCD, and raise a novel, yet untested assumption regarding perceptual deficits in OCD.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tiempo de Reacción
/
Análisis y Desempeño de Tareas
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Trastornos de la Memoria
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Memoria a Corto Plazo
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Trastorno Obsesivo Compulsivo
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Psychiatry Res
Año:
2017
Tipo del documento:
Article