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Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
Ciryam, Prajwal; Lambert-Smith, Isabella A; Bean, Daniel M; Freer, Rosie; Cid, Fernando; Tartaglia, Gian Gaetano; Saunders, Darren N; Wilson, Mark R; Oliver, Stephen G; Morimoto, Richard I; Dobson, Christopher M; Vendruscolo, Michele; Favrin, Giorgio; Yerbury, Justin J.
Afiliación
  • Ciryam P; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom; jyerbury@uow.edu.au prc9015@nyp.org.
  • Lambert-Smith IA; Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208-3500.
  • Bean DM; Department of Medicine, Columbia University College of Physicans & Surgeons, New York, NY 10032-3784.
  • Freer R; Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
  • Cid F; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522 Australia.
  • Tartaglia GG; School of Biological Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW 2522 Australia.
  • Saunders DN; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
  • Wilson MR; Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
  • Oliver SG; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.
  • Morimoto RI; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.
  • Dobson CM; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
  • Vendruscolo M; Universitat Pompeu Fabra, 08003 Barcelona, Spain.
  • Favrin G; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
  • Yerbury JJ; Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Proc Natl Acad Sci U S A ; 114(20): E3935-E3943, 2017 05 16.
Article en En | MEDLINE | ID: mdl-28396410
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Nervios Espinales / Agregación Patológica de Proteínas / Esclerosis Amiotrófica Lateral Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Nervios Espinales / Agregación Patológica de Proteínas / Esclerosis Amiotrófica Lateral Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article