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Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Weber, Helga; Valbuena, José R; Barbhuiya, Mustafa A; Stein, Stefan; Kunkel, Hana; García, Patricia; Bizama, Carolina; Riquelme, Ismael; Espinoza, Jaime A; Kurtz, Stephen E; Tyner, Jeffrey W; Calderon, Juan Francisco; Corvalán, Alejandro H; Grez, Manuel; Pandey, Akhilesh; Leal-Rojas, Pamela; Roa, Juan C.
Afiliación
  • Weber H; Center of Excellence in Traslational Medicine (CEMT) and Scientific and Technological Bioresource Nucleus (BIOREN), Universidad de La Frontera, Temuco, Chile.
  • Valbuena JR; Department of Pathology, Faculty of Medicine, Temuco, Chile.
  • Barbhuiya MA; Department of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Stein S; McKusick-Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Kunkel H; Gene Therapy Unit, Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • García P; Gene Therapy Unit, Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Bizama C; Department of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Riquelme I; Center for Investigation in Translational Oncology (CITO), Advanced Center for Chronic Diseases (ACCDiS), Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Espinoza JA; Department of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Kurtz SE; Center for Investigation in Translational Oncology (CITO), Advanced Center for Chronic Diseases (ACCDiS), Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Tyner JW; Center of Excellence in Traslational Medicine (CEMT) and Scientific and Technological Bioresource Nucleus (BIOREN), Universidad de La Frontera, Temuco, Chile.
  • Calderon JF; Department of Pathology, Faculty of Medicine, Temuco, Chile.
  • Corvalán AH; SciLifeLab, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Stockholm, Sweden.
  • Grez M; Division of Hematology and Medical Oncology, Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Pandey A; Division of Hematology and Medical Oncology, Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Leal-Rojas P; Center for Genetics and Genomics, School of Medicine, Clínica Alemana de Santiago - Universidad del Desarrollo, Santiago, Chile.
  • Roa JC; Center for Investigation in Translational Oncology (CITO), Advanced Center for Chronic Diseases (ACCDiS), Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Oncotarget ; 8(16): 26169-26184, 2017 Apr 18.
Article en En | MEDLINE | ID: mdl-28412732
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Benzoquinonas / Proteínas HSP90 de Choque Térmico / Lactamas Macrocíclicas / Descubrimiento de Drogas / Antineoplásicos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Chile
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Benzoquinonas / Proteínas HSP90 de Choque Térmico / Lactamas Macrocíclicas / Descubrimiento de Drogas / Antineoplásicos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Chile