Self-recognition of the racemic ligand in the formation of homochiral dinuclear V(V) complex: In vitro anticancer activity, DNA and HSA interaction.

Kazemi, Zahra; Amiri Rudbari, Hadi; Mirkhani, Valiollah; Sahihi, Mehdi; Moghadam, Majid; Tangestaninejad, Shahram; Mohammadpoor-Baltork, Iraj; Kajani, Abolghasem Abbasi; Azimi, Gholamhassan

Self-recognition of the racemic ligand in the formation of homochiral dinuclear V(V) complex: In vitro anticancer activity, DNA and HSA interaction.

Kazemi, Zahra; Amiri Rudbari, Hadi; Mirkhani, Valiollah; Sahihi, Mehdi; Moghadam, Majid; Tangestaninejad, Shahram; Mohammadpoor-Baltork, Iraj; Kajani, Abolghasem Abbasi; Azimi, Gholamhassan.

Afiliación

Kazemi Z; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Amiri Rudbari H; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran. Electronic address: h.a.rudbari@sci.ui.ac.ir.
Mirkhani V; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran. Electronic address: mirkhani@sci.ui.ac.ir.
Sahihi M; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Moghadam M; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Tangestaninejad S; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Mohammadpoor-Baltork I; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Kajani AA; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.
Azimi G; Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran.

Eur J Med Chem ; 135: 230-240, 2017 Jul 28.

Article en En | MEDLINE | ID: mdl-28456032

Asunto(s)

Antineoplásicos/farmacología; ADN de Neoplasias/efectos de los fármacos; Compuestos Organometálicos/farmacología; Albúmina Sérica/antagonistas & inhibidores; Vanadio/farmacología; Antineoplásicos/síntesis química; Antineoplásicos/química; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; ADN de Neoplasias/química; Relación Dosis-Respuesta a Droga; Ensayos de Selección de Medicamentos Antitumorales; Fibroblastos/efectos de los fármacos; Células HeLa; Humanos; Ligandos; Células MCF-7; Simulación del Acoplamiento Molecular; Compuestos Organometálicos/síntesis química; Compuestos Organometálicos/química; Albúmina Sérica/química; Relación Estructura-Actividad; Vanadio/química

Palabras clave

DNA- and HSA-binding; Dinuclear vanadium complex; Homochiral metal complex; In vitro assay; Self-recognition

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos Organometálicos / Vanadio / ADN de Neoplasias / Albúmina Sérica / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2017 Tipo del documento: Article País de afiliación: Irán

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