In Vivo Demonstration of PSMA Expression in Adenocarcinoma Urinary Bladder Using 68Ga-PSMA 11 PET/CT.
Clin Nucl Med
; 42(7): 542-543, 2017 Jul.
Article
en En
| MEDLINE
| ID: mdl-28481793
ABSTRACT
In vitro and in vivo studies have demonstrated prostate-specific membrane antigen (PSMA) expression in various malignant and benign tumors. Based on the recent immunohistochemical study showing PSMA expression in adenocarcinoma of urinary bladder, we hypothesized that PSMA expression in adenocarcinoma of urinary bladder can be demonstrated in vivo using Ga-PSMA 11 PET/CT. We present a man with exstrophy bladder, presenting with adenocarcinoma urinary bladder referred for staging PET/CT. Both F-FDG and Ga-PSMA-11 PET/CT were done, which showed PSMA expression in the primary tumor as well as metastatic lymph nodes.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
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Neoplasias de la Vejiga Urinaria
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Adenocarcinoma
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Regulación Neoplásica de la Expresión Génica
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Glutamato Carboxipeptidasa II
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Tomografía Computarizada por Tomografía de Emisión de Positrones
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Antígenos de Superficie
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Nucl Med
Año:
2017
Tipo del documento:
Article
País de afiliación:
India