PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection.

Cayatte, Corinne; Marin, Alexander; Rajani, Gaurav Manohar; Schneider-Ohrum, Kirsten; Snell Bennett, Angie; Marshall, Jason D; Andrianov, Alexander K

Cayatte, Corinne; Marin, Alexander; Rajani, Gaurav Manohar; Schneider-Ohrum, Kirsten; Snell Bennett, Angie; Marshall, Jason D; Andrianov, Alexander K.

Afiliación

Cayatte C; Infectious Disease/Vaccines Department, MedImmune , Gaithersburg, Maryland 20878, United States.
Marin A; Institute for Bioscience and Biotechnology Research, University of Maryland , Rockville, Maryland 20850, United States.
Rajani GM; Infectious Disease/Vaccines Department, MedImmune , Gaithersburg, Maryland 20878, United States.
Schneider-Ohrum K; Infectious Disease/Vaccines Department, MedImmune , Gaithersburg, Maryland 20878, United States.
Snell Bennett A; Infectious Disease/Vaccines Department, MedImmune , Gaithersburg, Maryland 20878, United States.
Marshall JD; Infectious Disease/Vaccines Department, MedImmune , Gaithersburg, Maryland 20878, United States.
Andrianov AK; Institute for Bioscience and Biotechnology Research, University of Maryland , Rockville, Maryland 20850, United States.

Mol Pharm ; 14(7): 2285-2293, 2017 07 03.

Article en En | MEDLINE | ID: mdl-28544850

Asunto(s)

Compuestos Organofosforados/química; Polímeros/química; Virus Sincitiales Respiratorios/inmunología; Animales; Anticuerpos Neutralizantes/sangre; Anticuerpos Neutralizantes/inmunología; Células CHO; Dicroismo Circular; Cricetulus; Ensayo de Inmunoadsorción Enzimática; Humanos; Inmunidad Celular/inmunología; Inmunoglobulina G/sangre; Inmunoglobulina G/inmunología; Ratones; Ratones Endogámicos BALB C; Virus Sincitiales Respiratorios/metabolismo; Vacunas Virales/química; Vacunas Virales/inmunología

Palabras clave

complexation; immunoadjuvants; polyphosphazenes; respiratory syncytial virus; self-assembly; vaccine delivery; vaccines

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos Organofosforados / Polímeros / Virus Sincitiales Respiratorios Límite: Animals / Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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