Elevating 4-hydroxycoumarin production through alleviating thioesterase-mediated salicoyl-CoA degradation.

Shen, Xiaolin; Mahajani, Monika; Wang, Jia; Yang, Yaping; Yuan, Qipeng; Yan, Yajun; Lin, Yuheng

Shen, Xiaolin; Mahajani, Monika; Wang, Jia; Yang, Yaping; Yuan, Qipeng; Yan, Yajun; Lin, Yuheng.

Afiliación

Shen X; State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Mahajani M; BiotecEra Inc., Athens, GA 30602, USA.
Wang J; State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Yang Y; College of Engineering, The University of Georgia, Athens, GA 30602, USA.
Yuan Q; State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Yan Y; College of Engineering, The University of Georgia, Athens, GA 30602, USA. Electronic address: yajunyan@uga.edu.
Lin Y; BiotecEra Inc., Athens, GA 30602, USA. Electronic address: yuheng.lin@biotecera.com.

Metab Eng ; 42: 59-65, 2017 07.

Article en En | MEDLINE | ID: mdl-28587908

Asunto(s)

4-Hidroxicumarinas/biosíntesis; Escherichia coli/metabolismo; Palmitoil-CoA Hidrolasa/biosíntesis; Escherichia coli/genética; Palmitoil-CoA Hidrolasa/genética

Palabras clave

4-Hydoxycoumarin; Acyl-CoAs; Salicoyl-CoA degradation; Thioester; Thioesterase

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Palmitoil-CoA Hidrolasa / Escherichia coli / 4-Hidroxicumarinas Idioma: En Revista: Metab Eng Asunto de la revista: ENGENHARIA BIOMEDICA / METABOLISMO Año: 2017 Tipo del documento: Article País de afiliación: China

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