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Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis.
Machlus, Kellie R; Wu, Stephen K; Vijey, Prakrith; Soussou, Thomas S; Liu, Zhi-Jian; Shacham, Eran; Unger, T J; Kashyap, Trinayan; Klebanov, Boris; Sola-Visner, Martha; Crochiere, Marsha; Italiano, Joseph E; Landesman, Yosef.
Afiliación
  • Machlus KR; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Wu SK; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Vijey P; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Soussou TS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Liu ZJ; Department of Pediatrics, Harvard Medical School, Boston, MA.
  • Shacham E; Division of New Born Medicine, Boston Children's Hospital, Boston, MA.
  • Unger TJ; Karyopharm Therapeutics, Newton, MA; and.
  • Kashyap T; Karyopharm Therapeutics, Newton, MA; and.
  • Klebanov B; Karyopharm Therapeutics, Newton, MA; and.
  • Sola-Visner M; Karyopharm Therapeutics, Newton, MA; and.
  • Crochiere M; Department of Pediatrics, Harvard Medical School, Boston, MA.
  • Italiano JE; Division of New Born Medicine, Boston Children's Hospital, Boston, MA.
  • Landesman Y; Karyopharm Therapeutics, Newton, MA; and.
Blood ; 130(9): 1132-1143, 2017 08 31.
Article en En | MEDLINE | ID: mdl-28630120
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trombocitopenia / Trombopoyetina / Triazoles / Megacariocitos / Transducción de Señal / Trombopoyesis / Hidrazinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Blood Año: 2017 Tipo del documento: Article País de afiliación: Marruecos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trombocitopenia / Trombopoyetina / Triazoles / Megacariocitos / Transducción de Señal / Trombopoyesis / Hidrazinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Blood Año: 2017 Tipo del documento: Article País de afiliación: Marruecos