Thalamic deep brain stimulation for orthostatic tremor: A multicenter international registry.
Mov Disord
; 32(8): 1240-1244, 2017 Aug.
Article
en En
| MEDLINE
| ID: mdl-28631862
ABSTRACT
BACKGROUND:
We report the accumulated experience with ventral intermediate nucleus deep brain stimulation for medically refractory orthostatic tremor.METHODS:
Data from 17 patients were reviewed, comparing presurgical, short-term (0-48 months), and long-term (≥48 months) follow-up. The primary end point was the composite activities of daily living/instrumental activities of daily living score. Secondary end points included latency of symptoms on standing and treatment-related complications.RESULTS:
There was a 21.6% improvement (P = 0.004) in the composite activities of daily living/instrumental activities of daily living score, which gradually attenuated (12.5%) in the subgroup of patients with an additional long-term follow-up (8 of 17). The latency of symptoms on standing significantly improved, both in the short-term (P = 0.001) and in the long-term (P = 0.018). Three patients obtained no/minimal benefit from the procedure.CONCLUSIONS:
Deep brain stimulation of the ventral intermediate nucleus was, in general, safe and well tolerated, yielding sustained benefit in selected patients with medically refractory orthostatic tremor. © 2017 International Parkinson and Movement Disorder Society.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Temblor
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Sistema de Registros
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Núcleos Talámicos Ventrales
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Estimulación Encefálica Profunda
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Mareo
Tipo de estudio:
Observational_studies
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Prognostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Mov Disord
Asunto de la revista:
NEUROLOGIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Estados Unidos