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Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis.
Luangmonkong, Theerut; Suriguga, Su; Bigaeva, Emilia; Boersema, Miriam; Oosterhuis, Dorenda; de Jong, Koert P; Schuppan, Detlef; Mutsaers, Henricus A M; Olinga, Peter.
Afiliación
  • Luangmonkong T; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands.
  • Suriguga S; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
  • Bigaeva E; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands.
  • Boersema M; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands.
  • Oosterhuis D; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands.
  • de Jong KP; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands.
  • Schuppan D; Department of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, The Netherlands.
  • Mutsaers HAM; Institute of Translational Immunology and Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany.
  • Olinga P; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Br J Pharmacol ; 174(18): 3107-3117, 2017 Sep.
Article en En | MEDLINE | ID: mdl-28691737

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Quinolinas / Proteína Smad2 / Cirrosis Hepática Límite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Quinolinas / Proteína Smad2 / Cirrosis Hepática Límite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos