ABT-263 induces G<sub>1</sub>/G<sub>0</sub>-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro.

Lin, Qing-Huan; Que, Fu-Chang; Gu, Chun-Ping; Zhong, De-Sheng; Zhou, Dan; Kong, Yi; Yu, Le; Liu, Shu-Wen

ABT-263 induces G₁/G₀-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro.

Lin, Qing-Huan; Que, Fu-Chang; Gu, Chun-Ping; Zhong, De-Sheng; Zhou, Dan; Kong, Yi; Yu, Le; Liu, Shu-Wen.

Afiliación

Lin QH; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Que FC; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Gu CP; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhong DS; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhou D; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Kong Y; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Yu L; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Liu SW; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.

Acta Pharmacol Sin ; 38(12): 1632-1641, 2017 Dec.

Article en En | MEDLINE | ID: mdl-28713162

Asunto(s)

Compuestos de Anilina/farmacología; Antineoplásicos/farmacología; Apoptosis/efectos de los fármacos; Autofagia/efectos de los fármacos; Neoplasias Esofágicas/tratamiento farmacológico; Neoplasias Esofágicas/patología; Puntos de Control de la Fase G1 del Ciclo Celular/efectos de los fármacos; Fase de Descanso del Ciclo Celular/efectos de los fármacos; Sulfonamidas/farmacología; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Relación Dosis-Respuesta a Droga; Ensayos de Selección de Medicamentos Antitumorales; Humanos; Relación Estructura-Actividad; Células Tumorales Cultivadas

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Sulfonamidas / Neoplasias Esofágicas / Fase de Descanso del Ciclo Celular / Apoptosis / Puntos de Control de la Fase G1 del Ciclo Celular / Compuestos de Anilina / Antineoplásicos Límite: Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: China

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