Rhodium(iii)-catalyzed and MeOH-involved regioselective mono-alkenylation of N-arylureas with acrylates.
Org Biomol Chem
; 15(34): 7088-7092, 2017 Aug 30.
Article
en En
| MEDLINE
| ID: mdl-28805855
ABSTRACT
We herein disclose, for the first time, Rh(iii)-catalyzed and MeOH-involved regioselective mono-alkenylation of arenes with acrylates using NHCONMe2 as the transformable directing group, giving direct access to diverse ortho-acrylated N-phenyl carbamates. The synthetic application of the obtained products to build privileged quinolin-2(1H)-ones and 3-(2-aminophenyl)acrylates has also been demonstrated in subsequent derivatization reactions.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Rodio
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Urea
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Acrilatos
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Metanol
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Alquenos
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
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QUIMICA
Año:
2017
Tipo del documento:
Article