Phase I clinical trials in patients with advanced non-small cell lung cancer treated within a Drug Development Unit: What have we learnt?

Capelan, Marta; Roda, Desamparados; Geuna, Elena; Rihawi, Karim; Bodla, Shankar; Kaye, Stan B; Bhosle, Jaishree; Banerji, Udai; O'Brien, Mary; de Bono, Johann S; Popat, Sanjay; Yap, Timothy A

Capelan, Marta; Roda, Desamparados; Geuna, Elena; Rihawi, Karim; Bodla, Shankar; Kaye, Stan B; Bhosle, Jaishree; Banerji, Udai; O'Brien, Mary; de Bono, Johann S; Popat, Sanjay; Yap, Timothy A.

Afiliación

Capelan M; Royal Marsden NHS Foundation Trust, London, United Kingdom.
Roda D; Royal Marsden NHS Foundation Trust, London, United Kingdom; The Institute of Cancer Research, London, United Kingdom.
Geuna E; Royal Marsden NHS Foundation Trust, London, United Kingdom.
Rihawi K; Royal Marsden NHS Foundation Trust, London, United Kingdom.
Bodla S; Royal Marsden NHS Foundation Trust, London, United Kingdom.
Kaye SB; Royal Marsden NHS Foundation Trust, London, United Kingdom; The Institute of Cancer Research, London, United Kingdom.
Bhosle J; Royal Marsden NHS Foundation Trust, London, United Kingdom.
Banerji U; Royal Marsden NHS Foundation Trust, London, United Kingdom; The Institute of Cancer Research, London, United Kingdom.
O'Brien M; Royal Marsden NHS Foundation Trust, London, United Kingdom.
de Bono JS; Royal Marsden NHS Foundation Trust, London, United Kingdom; The Institute of Cancer Research, London, United Kingdom.
Popat S; Royal Marsden NHS Foundation Trust, London, United Kingdom; National Heart and Lung Institute, Imperial College, London, United Kingdom.
Yap TA; Royal Marsden NHS Foundation Trust, London, United Kingdom; The Institute of Cancer Research, London, United Kingdom. Electronic address: timothy.yap@icr.ac.uk.

Lung Cancer ; 111: 6-11, 2017 09.

Article en En | MEDLINE | ID: mdl-28838399

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas/patología; Carcinoma de Pulmón de Células no Pequeñas/terapia; Neoplasias Pulmonares/patología; Neoplasias Pulmonares/terapia; Anciano; Anciano de 80 o más Años; Antineoplásicos/administración & dosificación; Antineoplásicos/efectos adversos; Antineoplásicos/uso terapéutico; Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico; Biomarcadores de Tumor; Carcinoma de Pulmón de Células no Pequeñas/mortalidad; Terapia Combinada/efectos adversos; Terapia Combinada/métodos; Femenino; Humanos; Neoplasias Pulmonares/mortalidad; Masculino; Persona de Mediana Edad; Terapia Molecular Dirigida; Clasificación del Tumor; Estadificación de Neoplasias; Oportunidad Relativa; Retratamiento; Resultado del Tratamiento

Palabras clave

NSCLC; Novel therapies; Phase I clinical trials

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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