Age-related adaptive responses of mitochondria of the retinal pigment epithelium to the everyday blue LED lighting.
Dokl Biol Sci
; 475(1): 141-143, 2017 Jul.
Article
en En
| MEDLINE
| ID: mdl-28861875
ABSTRACT
The effect of everyday blue light (λ = 440-460 nm) on mitochondria of the retinal pigment epithelium of different age groups of Japanese quail was studied using electron microscopy, morphometric methods, and biochemical analysis. We have found a significant increase in the number of mitochondria, including those modified, mainly in young birds. In addition, cell metabolic activity increased in response to blue lighting. These changes are assumed to reflect an adaptive response of mitochondria aimed at neutralizing the phototoxic effect of blue light caused by accumulation of lipofuscin granules.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Iluminación
/
Envejecimiento
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Coturnix
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Epitelio Pigmentado de la Retina
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Lipofuscina
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Mitocondrias
Límite:
Animals
Idioma:
En
Revista:
Dokl Biol Sci
Año:
2017
Tipo del documento:
Article
País de afiliación:
Rusia