Lewis Acid-Mediated Site-Selective Synthesis of Oxygenated Biaryls from Methoxyphenols and Electron-Rich Arenes.
J Org Chem
; 82(18): 9367-9383, 2017 09 15.
Article
en En
| MEDLINE
| ID: mdl-28862850
ABSTRACT
A rapid, efficient, and metal-free Lewis acid-mediated methodology has been developed for the site-selective synthesis of unsymmetrical oxygenated biaryls. This simple and efficient methodology furnished highly oxygenated and functionalized unsymmetrical biaryls in good to excellent yields by the direct oxidative coupling of electron-rich arenes to the α-position of carbonyl functionality of in situ generated masked benzoquinones.
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MEDLINE
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En
Revista:
J Org Chem
Año:
2017
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Article
País de afiliación:
India