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TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.
Chao, Yu-Kai; Schludi, Verena; Chen, Cheng-Chang; Butz, Elisabeth; Nguyen, O N Phuong; Müller, Martin; Krüger, Jens; Kammerbauer, Claudia; Ben-Johny, Manu; Vollmar, Angelika M; Berking, Carola; Biel, Martin; Wahl-Schott, Christian A; Grimm, Christian.
Afiliación
  • Chao YK; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Schludi V; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Chen CC; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Butz E; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Nguyen ONP; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Müller M; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Krüger J; High-Performance and Cloud Computing Group, Zentrum für Datenverarbeitung, Universität Tübingen, 72076 Tübingen, Germany.
  • Kammerbauer C; Department of Dermatology, Medical Faculty, Ludwig-Maximilians-Universität München, 80337 Munich, Germany.
  • Ben-Johny M; Calcium Signals Laboratory, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Vollmar AM; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Berking C; Department of Dermatology, Medical Faculty, Ludwig-Maximilians-Universität München, 80337 Munich, Germany.
  • Biel M; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Wahl-Schott CA; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany; christian.wahl@cup.uni-muenchen.de christian.grimm@cup.uni-muenchen.de.
  • Grimm C; Department of Pharmacy, Center for Drug Research and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, 81377 Munich, Germany; christian.wahl@cup.uni-muenchen.de christian.grimm@cup.uni-muenchen.de.
Proc Natl Acad Sci U S A ; 114(41): E8595-E8602, 2017 10 10.
Article en En | MEDLINE | ID: mdl-28923947
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polimorfismo Genético / Pigmentación / Canales de Calcio / Cabello Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polimorfismo Genético / Pigmentación / Canales de Calcio / Cabello Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: Alemania