Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality.
Org Biomol Chem
; 15(41): 8720-8728, 2017 Oct 25.
Article
en En
| MEDLINE
| ID: mdl-28932855
ABSTRACT
A series of thermally stable atropisomeric phencyclone ligands (ΔG > 35 kcal mol-1), bearing two chiral axes, has been successfully synthesized, taking into account the results of DFT calculations on model systems. The absolute configurations of the novel atropisomers have been assigned using TD-DFT simulation of ECD spectra. Atropisomeric phencyclones herein presented pave the way towards new ruthenium-based enantioselective hydrogenation catalysts.
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MEDLINE
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En
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Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
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QUIMICA
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2017
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Article