Synthesis of Indolizines via Palladium Catalyzed Annulation of Propargyl Carbonates and 2-(Pyridin-2-yl)acetonitrile Derivatives.
J Org Chem
; 82(20): 11304-11309, 2017 10 20.
Article
en En
| MEDLINE
| ID: mdl-28965400
ABSTRACT
A Pd-catalyzed regioselective annulation reaction of propargyl carbonates and 2-(pyridine-2-yl) acetonitrile derivatives has been accomplished, which provides a straightforward and efficient access to polysubstituted indolizines. The choice of the phosphine ligand is crucial to the high regio-selectivity of the reaction.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Paladio
/
Piridinas
/
Carbonatos
/
Indolizinas
Idioma:
En
Revista:
J Org Chem
Año:
2017
Tipo del documento:
Article