Increased Global Interaction Across Functional Brain Modules During Cognitive Emotion Regulation.
Cereb Cortex
; 28(9): 3082-3094, 2018 09 01.
Article
en En
| MEDLINE
| ID: mdl-28981646
ABSTRACT
Cognitive emotion regulation (CER) enables humans to flexibly modulate their emotions. While local theories of CER neurobiology suggest interactions between specialized local brain circuits underlying CER, e.g., in subparts of amygdala and medial prefrontal cortices (mPFC), global theories hypothesize global interaction increases among larger functional brain modules comprising local circuits. We tested the global CER hypothesis using graph-based whole-brain network analysis of functional MRI data during aversive emotional processing with and without CER. During CER, global between-module interaction across stable functional network modules increased. Global interaction increase was particularly driven by subregions of amygdala and cuneus-nodes of highest nodal participation-that overlapped with CER-specific local activations, and by mPFC and posterior cingulate as relevant connector hubs. Results provide evidence for the global nature of human CER, complementing functional specialization of embedded local brain circuits during successful CER.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Cognición
/
Emociones
/
Red Nerviosa
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Cereb Cortex
Asunto de la revista:
CEREBRO
Año:
2018
Tipo del documento:
Article
País de afiliación:
Alemania