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A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone.
Wang, L; Dehm, S M; Hillman, D W; Sicotte, H; Tan, W; Gormley, M; Bhargava, V; Jimenez, R; Xie, F; Yin, P; Qin, S; Quevedo, F; Costello, B A; Pitot, H C; Ho, T; Bryce, A H; Ye, Z; Li, Y; Eiken, P; Vedell, P T; Barman, P; McMenomy, B P; Atwell, T D; Carlson, R E; Ellingson, M; Eckloff, B W; Qin, R; Ou, F; Hart, S N; Huang, H; Jen, J; Wieben, E D; Kalari, K R; Weinshilboum, R M; Wang, L; Kohli, M.
Afiliación
  • Wang L; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA.
  • Dehm SM; Masonic Cancer Center, University of Minnesota, Minneapolis, USA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, USA; Department of Urology, University of Minnesota, Minneapolis, USA.
  • Hillman DW; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Sicotte H; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Tan W; Department of Medicine, Mayo Clinic, Jacksonville, USA.
  • Gormley M; Janssen Research and Development, Spring House, Philadelphia, USA.
  • Bhargava V; Janssen Research and Development, Spring House, Philadelphia, USA.
  • Jimenez R; Department of Pathology and Lab Medicine, Mayo Clinic, Rochester, USA.
  • Xie F; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA.
  • Yin P; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA.
  • Qin S; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA.
  • Quevedo F; Department of Oncology, Mayo Clinic, Rochester, USA.
  • Costello BA; Department of Oncology, Mayo Clinic, Rochester, USA.
  • Pitot HC; Department of Oncology, Mayo Clinic, Rochester, USA.
  • Ho T; Department of Medicine, Mayo Clinic, Scottsdale, USA.
  • Bryce AH; Department of Medicine, Mayo Clinic, Scottsdale, USA.
  • Ye Z; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA.
  • Li Y; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Eiken P; Department of Radiology, Mayo Clinic, Rochester, USA.
  • Vedell PT; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Barman P; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • McMenomy BP; Department of Radiology, Mayo Clinic, Rochester, USA.
  • Atwell TD; Department of Radiology, Mayo Clinic, Rochester, USA.
  • Carlson RE; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Ellingson M; Medical Genetics, Mayo Clinic, Rochester, USA.
  • Eckloff BW; Medical Genome Facility, Mayo Clinic, Rochester, USA.
  • Qin R; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Ou F; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Hart SN; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Huang H; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA.
  • Jen J; Medical Genome Facility, Mayo Clinic, Rochester, USA; Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, U
  • Wieben ED; Medical Genome Facility, Mayo Clinic, Rochester, USA.
  • Kalari KR; Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA.
  • Weinshilboum RM; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA.
  • Wang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA. Electronic address: wang.liewei@mayo.edu.
  • Kohli M; Department of Oncology, Mayo Clinic, Rochester, USA. Electronic address: kohli.manish@mayo.edu.
Ann Oncol ; 29(2): 352-360, 2018 02 01.
Article en En | MEDLINE | ID: mdl-29069303
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Prednisona / Resistencia a Antineoplásicos / Vía de Señalización Wnt / Neoplasias de la Próstata Resistentes a la Castración / Acetato de Abiraterona Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Prednisona / Resistencia a Antineoplásicos / Vía de Señalización Wnt / Neoplasias de la Próstata Resistentes a la Castración / Acetato de Abiraterona Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos