Large-scale purification of high purity &#945;1-antitrypsin from Cohn Fraction IV with virus inactivation by solvent/detergent and dry-heat treatment.

Huangfu, Chaoji; Zhang, Jinchao; Ma, Yuyuan; Jia, Junting; Li, Jingxuan; Lv, Maomin; Ma, Xiaowei; Zhao, Xiong; Zhang, Jingang

Large-scale purification of high purity α1-antitrypsin from Cohn Fraction IV with virus inactivation by solvent/detergent and dry-heat treatment.

Huangfu, Chaoji; Zhang, Jinchao; Ma, Yuyuan; Jia, Junting; Li, Jingxuan; Lv, Maomin; Ma, Xiaowei; Zhao, Xiong; Zhang, Jingang.

Afiliación

Huangfu C; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Zhang J; Lanzhou Center for Diseases Prevention and Control, Xining Joint Logistics Center, Lanzhou, People's Republic of China.
Ma Y; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Jia J; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Li J; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Lv M; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Ma X; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.
Zhao X; Hualan Biological Engineering Inc., Xinxiang, People's Republic of China.
Zhang J; Beijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, People's Republic of China.

Biotechnol Appl Biochem ; 65(3): 446-454, 2018 May.

Article en En | MEDLINE | ID: mdl-29072333

Asunto(s)

Proteínas Sanguíneas/química; Detergentes/farmacología; Calor; Solventes/farmacología; Inactivación de Virus/efectos de los fármacos; alfa 1-Antitripsina/aislamiento & purificación; Animales; Línea Celular; Detergentes/química; Virus de la Encefalomiocarditis/efectos de los fármacos; Herpesvirus Suido 1/efectos de los fármacos; Parvovirus/efectos de los fármacos; Solventes/química; Porcinos; Virus de la Estomatitis Vesicular Indiana/efectos de los fármacos; alfa 1-Antitripsina/química

Palabras clave

Cohn Fraction IV; blood product; chromatography; plasma protein; viral safety; α1-antitrypsin

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Solventes / Proteínas Sanguíneas / Alfa 1-Antitripsina / Inactivación de Virus / Detergentes / Calor Tipo de estudio: Qualitative_research Límite: Animals Idioma: En Revista: Biotechnol Appl Biochem Asunto de la revista: BIOQUIMICA / BIOTECNOLOGIA Año: 2018 Tipo del documento: Article

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