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PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.
Dickey, Audrey S; Sanchez, Dafne N; Arreola, Martin; Sampat, Kunal R; Fan, Weiwei; Arbez, Nicolas; Akimov, Sergey; Van Kanegan, Michael J; Ohnishi, Kohta; Gilmore-Hall, Stephen K; Flores, April L; Nguyen, Janice M; Lomas, Nicole; Hsu, Cynthia L; Lo, Donald C; Ross, Christopher A; Masliah, Eliezer; Evans, Ronald M; La Spada, Albert R.
Afiliación
  • Dickey AS; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Sanchez DN; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Arreola M; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Sampat KR; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Fan W; Gene Expression Laboratory, Salk Institute for Biological Studies, San Diego, CA 92037, USA.
  • Arbez N; Departments of Psychiatry, Neurology, and Pharmacology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Akimov S; Departments of Psychiatry, Neurology, and Pharmacology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Van Kanegan MJ; Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
  • Ohnishi K; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gilmore-Hall SK; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Flores AL; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Nguyen JM; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Lomas N; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Hsu CL; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Lo DC; Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
  • Ross CA; Departments of Psychiatry, Neurology, and Pharmacology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Masliah E; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Evans RM; Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.
  • La Spada AR; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
Sci Transl Med ; 9(419)2017 Dec 06.
Article en En | MEDLINE | ID: mdl-29212711
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tetrahidronaftalenos / PPAR delta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tetrahidronaftalenos / PPAR delta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos