Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases.

Sutavani, Ruhcha V; Phair, Iain R; Barker, Rebecca; McFarlane, Alison; Shpiro, Natalia; Lang, Stuart; Woodland, Andrew; Arthur, J Simon C

Sutavani, Ruhcha V; Phair, Iain R; Barker, Rebecca; McFarlane, Alison; Shpiro, Natalia; Lang, Stuart; Woodland, Andrew; Arthur, J Simon C.

Afiliación

Sutavani RV; From the Division of Cell Signalling and Immunology.
Phair IR; From the Division of Cell Signalling and Immunology.
Barker R; From the Division of Cell Signalling and Immunology.
McFarlane A; From the Division of Cell Signalling and Immunology.
Shpiro N; the MRC Protein Phosphorylation and Ubiquitylation Unit, and.
Lang S; the Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
Woodland A; the Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
Arthur JSC; From the Division of Cell Signalling and Immunology, j.s.c.arthur@dundee.ac.uk.

J Biol Chem ; 293(7): 2302-2317, 2018 02 16.

Article en En | MEDLINE | ID: mdl-29229781

Asunto(s)

Linfocitos B/metabolismo; Interleucina-10/metabolismo; Macrófagos/metabolismo; Proteínas Quinasas S6 Ribosómicas 90-kDa/metabolismo; Receptor Toll-Like 4/metabolismo; Animales; Células Cultivadas; Proteína de Unión a Elemento de Respuesta al AMP Cíclico/genética; Proteína de Unión a Elemento de Respuesta al AMP Cíclico/metabolismo; Femenino; Interleucina-10/genética; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Proteínas Quinasas S6 Ribosómicas 90-kDa/genética; Receptor Toll-Like 4/genética

Palabras clave

Interleukin 10; MSK1; RSK; Toll-like receptor 4 (TLR4); cAMP response element-binding protein (CREB); extracellular-signal-regulated kinase (ERK); p38 MAPK

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Interleucina-10 / Proteínas Quinasas S6 Ribosómicas 90-kDa / Receptor Toll-Like 4 / Macrófagos Límite: Animals Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article

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