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Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.
Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia; Hernandez, Dena G; Orme, Tatiana; Eicher, John D; Shepherd, Claire E; Parkkinen, Laura; Darwent, Lee; Heckman, Michael G; Scholz, Sonja W; Troncoso, Juan C; Pletnikova, Olga; Ansorge, Olaf; Clarimon, Jordi; Lleo, Alberto; Morenas-Rodriguez, Estrella; Clark, Lorraine; Honig, Lawrence S; Marder, Karen; Lemstra, Afina; Rogaeva, Ekaterina; St George-Hyslop, Peter; Londos, Elisabet; Zetterberg, Henrik; Barber, Imelda; Braae, Anne; Brown, Kristelle; Morgan, Kevin; Troakes, Claire; Al-Sarraj, Safa; Lashley, Tammaryn; Holton, Janice; Compta, Yaroslau; Van Deerlin, Vivianna; Serrano, Geidy E; Beach, Thomas G; Lesage, Suzanne; Galasko, Douglas; Masliah, Eliezer; Santana, Isabel; Pastor, Pau; Diez-Fairen, Monica; Aguilar, Miquel; Tienari, Pentti J; Myllykangas, Liisa; Oinas, Minna; Revesz, Tamas; Lees, Andrew; Boeve, Brad F.
Afiliación
  • Guerreiro R; UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal.
  • Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Kun-Rodrigues C; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Hernandez DG; Laboratory of Neurogenetics, National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA; German Center for Neurodegenerative Diseases, Tubingen, Germany.
  • Orme T; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Eicher JD; Merck & Co, Boston, MA, USA.
  • Shepherd CE; Neuroscience Research Australia, Sydney, NSW, Australia; School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Parkkinen L; Nuffield Department of Clinical Neurosciences, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Darwent L; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Heckman MG; Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL, USA.
  • Scholz SW; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
  • Troncoso JC; Department of Pathology (Neuropathology), Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Pletnikova O; Department of Pathology (Neuropathology), Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Ansorge O; Nuffield Department of Clinical Neurosciences, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Clarimon J; Memory Unit, Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
  • Lleo A; Memory Unit, Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
  • Morenas-Rodriguez E; Memory Unit, Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
  • Clark L; Taub Institute for Alzheimer Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
  • Honig LS; Taub Institute for Alzheimer Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
  • Marder K; Taub Institute for Alzheimer Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
  • Lemstra A; Department of Neurology and Alzheimer Center, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands.
  • Rogaeva E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, ON, Canada; Department of Medicine, University of Toronto, ON, Canada.
  • St George-Hyslop P; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, ON, Canada; Department of Medicine, University of Toronto, ON, Canada; Department of Clinical Neurosciences, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
  • Londos E; Clinical Memory Research Unit, Institution of Clinical Sciences Malmo, Lund University, Sweden.
  • Zetterberg H; UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg,
  • Barber I; Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Braae A; Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Brown K; Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Morgan K; Human Genetics, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
  • Troakes C; Department of Basic and Clinical Neuroscience and Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Al-Sarraj S; Department of Basic and Clinical Neuroscience and Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Lashley T; Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Holton J; Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Compta Y; Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Parkinson's Disease & Movement Disorders Unit, Neurology Service, Hospital Clinic, IDIBAPS, CIBERNED, Department of Biomedicine, University of Barcelona, Barcelona, S
  • Van Deerlin V; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Serrano GE; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Beach TG; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Lesage S; Inserm U1127, CNRS UMR7225, Sorbonne Universites, UPMC Univ Paris 06, UMR, Paris, France; S1127, Institut du Cerveau et de la Moelle epiniere, Paris, France.
  • Galasko D; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, La Jolla, CA, USA.
  • Masliah E; Laboratory of Neurogenetics, National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA; Division of Neurosciences, National Institutes of Health, Bethesda, MD, USA.
  • Santana I; Neurology Service, University of Coimbra Hospital, Coimbra, Portugal.
  • Pastor P; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain; Memory Unit, Department of Neurology, University Hospital Mutua de Terrassa, University of Barcelona, Barcelona, Spain; Fundacio de Docencia I Recerca Mutua de Terras
  • Diez-Fairen M; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain; Memory Unit, Department of Neurology, University Hospital Mutua de Terrassa, University of Barcelona, Barcelona, Spain; Fundacio de Docencia I Recerca Mutua de Terras
  • Aguilar M; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain; Memory Unit, Department of Neurology, University Hospital Mutua de Terrassa, University of Barcelona, Barcelona, Spain; Fundacio de Docencia I Recerca Mutua de Terras
  • Tienari PJ; Molecular Neurology, Research Programs Unit, University of Helsinki, Helsinki, Finland; Department of Neurology, Helsinki University Hospital, Helsinki, Finland.
  • Myllykangas L; Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki, Finland.
  • Oinas M; Department of Neurosurgery, University of Helsinki, Helsinki, Finland; Department of Neuropathology and Neurosurgery, Helsinki University Hospital, Helsinki, Finland.
  • Revesz T; Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Lees A; Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK.
  • Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Lancet Neurol ; 17(1): 64-74, 2018 01.
Article en En | MEDLINE | ID: mdl-29263008
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad por Cuerpos de Lewy / Estudio de Asociación del Genoma Completo Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Lancet Neurol Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Portugal
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad por Cuerpos de Lewy / Estudio de Asociación del Genoma Completo Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Lancet Neurol Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Portugal