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Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures.
Cervenka, Rene; Lukacs, Peter; Gawali, Vaibhavkumar S; Ke, Song; Koenig, Xaver; Rubi, Lena; Zarrabi, Touran; Hilber, Karlheinz; Sandtner, Walter; Stary-Weinzinger, Anna; Todt, Hannes.
Afiliación
  • Cervenka R; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Lukacs P; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Gawali VS; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Ke S; Department of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, UZA 2, A-1090, Vienna, Austria.
  • Koenig X; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Rubi L; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Zarrabi T; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Hilber K; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Sandtner W; Center for Physiology and Pharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
  • Stary-Weinzinger A; Department of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, UZA 2, A-1090, Vienna, Austria.
  • Todt H; Center for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria. hannes.todt@meduniwien.ac.at.
Sci Rep ; 8(1): 631, 2018 01 12.
Article en En | MEDLINE | ID: mdl-29330525
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Xenopus laevis / Canales de Sodio / Cisteína / Proteínas Musculares / Mutación Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Austria
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Xenopus laevis / Canales de Sodio / Cisteína / Proteínas Musculares / Mutación Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Austria