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Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Manfredsson, Fredric P; Luk, Kelvin C; Benskey, Matthew J; Gezer, Aysegul; Garcia, Joanna; Kuhn, Nathan C; Sandoval, Ivette M; Patterson, Joseph R; O'Mara, Alana; Yonkers, Reid; Kordower, Jeffrey H.
Afiliación
  • Manfredsson FP; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States; Mercy Health Saint Mary's, Grand Rapids, MI, United States. Electronic address: Fredric.manfredsson@hc.msu.edu.
  • Luk KC; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Benskey MJ; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
  • Gezer A; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States; DO/PHD Physician Scientist Training Program, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, United States.
  • Garcia J; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
  • Kuhn NC; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
  • Sandoval IM; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States; Mercy Health Saint Mary's, Grand Rapids, MI, United States.
  • Patterson JR; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States.
  • O'Mara A; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States; Undergraduate Neuroscience Program, Michigan State University, East Lansing, MI, United States.
  • Yonkers R; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States; Undergraduate Neuroscience Program, Michigan State University, East Lansing, MI, United States.
  • Kordower JH; Dept. of Neurological Science, Rush University Medical Center, Chicago, IL, United States; Center on Neurodegeneration, Van Andel Research Institute, Grand Rapids, MI, United States.
Neurobiol Dis ; 112: 106-118, 2018 04.
Article en En | MEDLINE | ID: mdl-29341898

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades del Sistema Nervioso Central / Sistema Nervioso Entérico / Alfa-Sinucleína / Enfermedades Gastrointestinales / Motilidad Gastrointestinal Límite: Animals / Humans / Male Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades del Sistema Nervioso Central / Sistema Nervioso Entérico / Alfa-Sinucleína / Enfermedades Gastrointestinales / Motilidad Gastrointestinal Límite: Animals / Humans / Male Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article