Prophylactic Antiheparanase Activity by PG545 Is Antiviral <i>In Vitro</i> and Protects against Ross River Virus Disease in Mice.

Supramaniam, Aroon; Liu, Xiang; Ferro, Vito; Herrero, Lara J

Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice.

Supramaniam, Aroon; Liu, Xiang; Ferro, Vito; Herrero, Lara J.

Afiliación

Supramaniam A; Institute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD, Australia.
Liu X; Institute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD, Australia.
Ferro V; School of Chemistry and Molecular Biosciences, the University of Queensland, Brisbane, QLD, Australia.
Herrero LJ; Australian Infectious Diseases Research Centre, the University of Queensland, Brisbane, QLD, Australia.

Antimicrob Agents Chemother ; 62(4)2018 04.

Article en En | MEDLINE | ID: mdl-29437628

Asunto(s)

Antiinflamatorios/uso terapéutico; Antivirales/uso terapéutico; Virus del Río Ross/efectos de los fármacos; Animales; Modelos Animales de Enfermedad; Ensayo de Inmunoadsorción Enzimática; Glucuronidasa/genética; Glucuronidasa/metabolismo; Ratones; Virus del Río Ross/enzimología; Virus del Río Ross/patogenicidad; Saponinas/uso terapéutico; Carga Viral/efectos de los fármacos

Palabras clave

GAGs mimetics; alphaviruses; anti-inflammatory; athritogenic; heparan sulfate mimetics

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / Virus del Río Ross / Antiinflamatorios Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Antimicrob Agents Chemother Año: 2018 Tipo del documento: Article País de afiliación: Australia

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